Friday, March 18, 2016

Turmeric: From Ancient Remedy to Modern Medicine



Turmeric: From ancient remedy to modern medicine

By: Ansley Rawlins
Turmeric, known in India as “the spice of life,” has been treasured for its curative properties for thousands of years, particularly in Ayurveda (one of the oldest holistic healing modalities in the world); yet modern research is only just beginning to confirm its medicinal value. Recent studies have shown that curcumin, the primary active compound in turmeric, is a powerful antioxidant responsible for turmeric’s many health benefits. As further studies are conducted, more and more uses for turmeric are coming to light.
   Anti-inflammatory properties: Numerous studies have made it clear that curcumin is highly effective as an anti-inflammatory - perhaps even more so than standard NSAID pain medications. In one such study, osteoarthritis patients had a 58% decrease in pain & stiffness after 90 days taking a concentrated form of curcumin. It is suggested that curcumin inhibits expression of the “pain enzyme” COX-2, thus reducing the body’s inflammatory response in much the same way as drugs such as ibuprofen.
   Anti-carcinogenic: Curcumin helps prevent cancer by inhibiting both the formation and propagation of free-radicals. Some studies indicate it can slow or stop the growth of existing cancers, and may even destroy cancer cells.
   Antibacterial, anti-fungal, antiviral: Thanks to these properties, turmeric/ curcumin can boost the immune system, and is also valuable as an antiseptic. It helps ward off many types of infection, both internally and externally; when applied directly, turmeric enhances external wound healing and decreases recovery time.
   Enhanced liver function: May help protect against liver damage.
   Improved heart health: Turmeric use can lower cholesterol and blood pressure 
over time, and reduces the risk of heart disease.
   Beneficial to the digestive tract: Turmeric is closely related to ginger, and has 
many of the same effects for digestive issues.
   Helps with glucose control: May help prevent and control diabetes (type 2) by 
improving the body’s ability to moderate insulin levels and glucose control, 
reducing insulin resistance, and lowering blood glucose levels.
   Neurodegenerative disease prevention: Curcumin inhibits the formation of 
amyloid beta plaques, reduces oxidative damage, and delays or inhibits the degradation of neurons in the brain. Several promising studies have been conducted on the effects of curcumin on Alzheimer’s disease, which is caused in part by the accumulation of amyloid beta protein plaques in the brain. There is also a link between Alzheimer’s and the presence of inflammatory substances that accompany the plaque deposition. Prolonged use of NSAIDs has previously been shown to reduce the chances of developing Alzheimer’s, but at the risk of causing the kidney, liver, and GI tract damage. Curcumin’s potent anti- inflammatory effects are similarly beneficial in reducing Alzheimer’s, without toxicity. Additionally, the anti-oxidative properties of curcumin help it fight the free radicals that cause neuron deterioration responsible for disorders such as Alzheimer’s, Parkinson’s, and Huntington’s disease.
   Effective antidepressant: Oxidative damage by free radicals and increased activation of inflammatory molecules such as T-cells, monocytes, and neutrophils (from oxidative stress) are hallmarks of Major Depression (considered a neurodegenerative disorder). The increase in inflammatory molecules is believed to be caused by reduced levels of antioxidants and antioxidant enzymes.
                  −  Malondialdehyde, a byproduct of damage to fatty acids in cell membranes, can be measured in blood samples, thus making it a suitable biomarker for oxidative stress. By measuring these levels before and after administration of curcumin, the antioxidant property can be shown in study participants with depression.
                  −  It is by reducing oxidative stress in the body that curcumin also achieves its potency as an anti-inflammatory.
                  −  Additionally, curcumin is highly effective at helping modulate neurotransmitters (serotonin, dopamine, & norepinephrine) in the brain. These are what help control mood, motivation, pleasure, cognition, and stress, among other things. The imbalance of these three in depression is believed to be caused by an overabundance of monoamine oxidase (MAO), the enzyme responsible for inactivation of serotonin, dopamine, & norepinephrine. Curcumin inhibits MAOs, thus inhibiting excessive re- uptake of neurotransmitters and allowing them to reach more balanced levels. This leads to increased levels of serotonin, which thereby causes improved mood and reduced depression.
                  −  In 2013, a study conducted by researchers at the Department of Pharmacology of Government Medical College in Bhavnagar, Gujarat, India, showed curcumin to be as effective as fluoxetine (Prozac) at treating depression, without the negative side effects (such as increased suicidal ideation) common to fluoxetine and other standard antidepressants. The study had three groups; one was given 10mg/day fluoxetine, another was given 1000mg/day curcumin, and the third was given a combination. All three groups showed similar improvement over the course of the study.
                  −  Another study researched the effects of combining curcumin with antidepressant drugs and found that there can be a synergistic effect on increased serotonin. Study groups that were given curcumin in combination with drugs like fluoxetine, venlafaxine (Effexor), and bupropion (Wellbutrin) showed greater increases in serotonin levels than groups treated with drugs or curcumin alone.
   Bioavailability of curcumin in turmeric: Curcumin alone has difficulty being absorbed into the bloodstream, so ordinary dried turmeric, on its own, would need to be taken in fairly large quantities to achieve the desired therapeutic effect. This is remedied with a few easy solutions. Firstly, curcumin is a fat- soluble compound, so combining turmeric with any fat or oil significantly increases the body’s absorption of curcumin. Secondly, it has been proven that curcumin is absorbed up to 1000 times better when combined with certain other compounds - including piperine, the compound that gives black pepper its distinct taste. Thus another easy way to greatly increase curcumin’s bioavailability is by simply combining turmeric and black pepper. Thirdly, fresh turmeric contains natural oils, so when fresh turmeric root is used, it provides sufficient lipids to increase the body’s uptake of curcumin.
One of the primary ways of consuming turmeric for health in Ayurveda is Golden Milk. Traditionally it was made with coconut milk, which, in addition to providing enough lipids for good curcumin absorption, has many of its own health benefits that compliment turmeric’s quite nicely. It is rich in antioxidants and nutrients such as Vitamins B, C, E, magnesium, potassium, phosphorus, and iron. Fifty percent of the fat content in coconut milk is a medium-chain fatty acid (MCFA), lauric acid. The body converts lauric acid to a monoglyceride capable of destroying certain viruses (measles, influenza, herpes, etc.). Lauric acid, like other MCFAs, is easily digested, readily crosses cell membranes, and upon reaching the liver is immediately converted into energy, rather than being stored as fat.
Making Golden Milk or Turmeric Teas:
Methods for making Golden Milk from turmeric vary, but there are two basic ways of preparing a base from which to prepare future servings. One is by making a turmeric paste, the other by making a powder mix.
Turmeric Paste:
1/2 cup turmeric powder (appx. 96 grams) or slightly less fresh turmeric 1 tablespoon ground black pepper
1 cup water
1 tablespoon to 1/4 cup coconut oil (or ghee, or butter)
(optional: up to 2 tablespoons each ground ginger and/or ground clove)
Bring all except coconut oil to a low simmer, stirring, until it becomes a thick paste. Remove from heat.
Whisk in enough coconut oil to form a softer paste.
Refrigerated, can be kept several weeks.
Turmeric Powder Mix:
Same quantities of dried spices as above, combined & stored in a jar.
Golden Milk:
1/2 to 1 teaspoon turmeric mix (if powder, also add 1tsp to 1Tbsp coconut oil) 1 cup milk or water
Any additional desired spices
Bring to a low simmer, stir for a few minutes, and remove from heat.
Cool slightly before adding honey to taste (heat destroys some of the beneficial properties of honey).
Strain with a very fine mesh strainer, coffee filter, or reusable coffee filter before serving (or contain spices in a cotton tea/mulling bag before simmering).
Suggested additional spices and flavourings: cayenne, cinnamon, cardamom, nutmeg, allspice, vanilla (vanilla soymilk is really nice as the milk base), lemon juice, a slice of orange, an apple slice, sliced cucumber.

Ansley Rawlins is a blogger, social/environmental activist and health enthusiast based out of Charlotte North Carolina. If you have any questions regarding this article please visit Mahogany's vision: Social & Environmental Advocacy Facebook page https://www.facebook.com/search/top/?q=mahoganys%20vision%20social%20%20environmental%20advocacy

No comments:

Post a Comment